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Multivariate signal integration
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Multivariate signal integration
Nat Rev Mol Cell Biol. 2010 May 6. [Epub ahead of print]
Linding R
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systems biology
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LindingLab@DTU
LindingLab@ICR [work from 2007-2010]
DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization.
(R)evolution of Complex Regulatory Systems
Multivariate signal integration
Roles of "junk phosphorylation" in modulating biomolecular association of phosphorylated proteins?
Simplistic pathways or complex networks?
Cell-Specific Information Processing in Segregating Populations of Eph Receptor Ephrin–Expressing Cells.
Network-based drugs and biomarkers.
Experimental and computational tools useful for (re)construction of dynamic kinase-substrate networks.
Phosphorylation dynamics during early differentiation of human embryonic stem cells.
Comparative analysis reveals conserved protein phosphorylation networks implicated in multiple diseases.
Positive selection of tyrosine loss in metazoan evolution.
Dissecting the interface between signaling and transcriptional regulation in human B cells.
Dynamic modularity in protein interaction networks predicts breast cancer outcome.
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G(2)/M DNA Damage Checkpoint.
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds.
Linear motif atlas for phosphorylation-dependent signaling.
Network medicine.
Directional and quantitative phosphorylation networks.
SLRI & MIT [work from 2005-2007]
EMBL [work from 2000-2004]
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