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Selected Publications

Collection of selected publications
Cell-Specific Information Processing in Segregating Populations of Eph Receptor Ephrin–Expressing Cells.
Science. 2009 Dec 11;326(5959):1502-9.
Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells
Scientists have discovered how genetic cancer mutations systematically attack the networks controlling human cells, knowledge critical for the future development of personalized precision cancer treatments.
Protein disorder prediction: implications for structural proteomics.
Structure. 2003 Nov;11(11):1453-9.
Systematic discovery of new recognition peptides mediating protein interaction networks.
PLoS Biol. 2005 Dec;3(12):e405. Epub 2005 Nov 15.
ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins.
Nucleic Acids Res. 2003 Jul 1;31(13):3625-30.
GlobPlot: Exploring protein sequences for globularity and disorder.
Nucleic Acids Res. 2003 Jul 1;31(13):3701-8.
Synthetic modular systems - reverse engineering of signal transduction.
FEBS Lett. 2005 Mar 21;579(8):1808-14.
Navigating cancer network attractors for tumor-specific therapy
Nature Biotechnology 30, 842–848 (2012)
Cells, shared memory and breaking the PTM code
Molecular Systems Biology 8 Article number: 598 doi:10.1038/msb.2012.33
Network Medicine Strikes a Blow against Breast Cancer
Cell. 2012 May 11;149(4):731-3.
Response to Comment on “Positive Selection of Tyrosine Loss in Metazoan Evolution”
Science 20 May 2011: Vol. 332 no. 6032 p. 917
Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling.
Cell. 2015 Sep 16. pii: S0092-8674(15)01108-3. doi: 10.1016/j.cell.2015.08.056.
Unmasking Determinants of Specificity in the Human Kinome.
Cell. 2015 Sep 16. pii: S0092-8674(15)01109-5. doi: 10.1016/j.cell.2015.08.057.
Systematic discovery of in vivo phosphorylation networks.
Cell. 2007 Jun 29;129(7):1415-26. Epub 2007 Jun 14.
Linear motif atlas for phosphorylation-dependent signaling.
Sci Signal. 2008 Sep 2;1(35):ra2.
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds.
Science. 2008 Oct 17;322(5900):453-6.
Positive selection of tyrosine loss in metazoan evolution.
Science. 2009 Sep 25;325(5948):1686-8. Epub 2009 Jul 9.
Comparative analysis reveals conserved protein phosphorylation networks implicated in multiple diseases.
Sci Signal. 2009 Jul 28;2(81):ra39.
Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments
Cell Reports 2017 Sep 19;20(12):2784-2791. doi: 10.1016/j.celrep.2017.08.095.
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